We have to help him realize the beauty of his being is a gift from God. When you change this, you will never find true happiness, but a dark illusion. The trees, flowers, and animals in God's creation are beautifully made, and any alterations or genetic engineering would be an insult to Him.
We need to encourage him to grow in humility and contentment. We need to accept the wise creation of God in our life even with our limitations. Importantly, we need to pray for him, especially his soul which needs dire protection from the works of evil.